Physical Activity and Type 2 Diabetes : Therapeutic Effects and Mechanisms of Action

Physical Activity and Type 2 Diabetes : Therapeutic Effects and Mechanisms of Action
ISBN: 9780736064798
Publication Date: 18 April 2008

Over the past 50 years, there has been a dramatic increase in the prevalence of interrelated metabolic disease states, including obesity, insulin resistance, and type 2 diabetes mellitus. In modern Western nations, the population-based prevalence of insulin resistance is approaching 20%, and type 2 diabetes is now the most common endocrine disorder in adults. No longer a disease reserved for the aging population, type 2 diabetes is also on the rise in adolescents. Approximately 30% of all newly diagnosed cases (between 1982 and 1994 in the United States alone) are among people 10 to 19 years of age.

For those engaged in a struggle against this modern-day epidemic, Physical Activity and Type 2 Diabetes provides cutting-edge research to energize current efforts in diabetes prevention, management, and treatment. The most in-depth and up-to-date book on the topic, Physical Activity and Type 2 Diabetes presents a series of independent but related chapters authored by the foremost researchers of insulin resistance examining topics such as these:

-Physical inactivity as a primary cause for the rising incidence of insulin resistance

-The emergence of an “exercise-deficient” phenotype

-The effects of exercise training on selected aspects of substrate metabolism

-The role of endurance and resistance training programs for the prevention and treatment of insulin resistance

-The identification of new molecular targets and pathways useful for the treatment of insulin resistance and type 2 diabetes.
Physical Activity and Type 2 Diabetes provides a four-part, in-depth examination of the relational nature of diabetes and physical activity. Part I begins with a description of the scope and extent of the “...